https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53567 Wed 28 Feb 2024 16:32:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50502 Wed 28 Feb 2024 16:06:30 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45053 Wed 26 Oct 2022 12:04:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48158 Wed 24 Apr 2024 11:38:58 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30810 Wed 23 Feb 2022 16:04:14 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43541 Wed 21 Sep 2022 12:42:25 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33091 Wed 17 Nov 2021 16:30:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38852 P =.001), whereas those treated with CRT were more likely to have internal HNL only (74% vs 25%, P =.001). Conclusions: Chronic HNL is highly prevalent following multimodal treatment, and differences in HNL presentations exist between treatment modalities.]]> Wed 16 Feb 2022 15:27:31 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40474 Wed 13 Mar 2024 08:52:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12931 Wed 11 Apr 2018 17:11:41 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30823 Wed 11 Apr 2018 16:53:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26276 Wed 11 Apr 2018 16:11:50 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20396 Wed 11 Apr 2018 15:20:35 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16544 Wed 11 Apr 2018 14:53:25 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20481 Wed 11 Apr 2018 14:29:37 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29497 Wed 11 Apr 2018 12:30:49 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27665 Wed 11 Apr 2018 12:19:59 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22616 30 kg/m2) was significantly associated with the prevalence of knee (OR: 4.37; 95 % CI: 2.08,9.20) and hip (OR: 2.52; 95 % CI: 1.17,5.43) OA. Individuals who stand or walk a lot, but do not carry or lift things during their occupational activities were 2.0 times less likely to have hip OA (OR: 0.50; 95 % CI: 0.26,0.96). Individuals who usually lift or carry light loads or have to climb stairs or hills were 2.2 times less likely to have hip OA (OR: 0.45; 95 % CI: 0.21,0.95). The odds of having hip OA were 1.9 times lower in individuals consuming recommended or higher vitamin C intake (OR: 0.52; 95 % CI: 0.29,0.96). Significant differences in prevalence were found for both males and females across age categories. Conclusion: The prevalence of knee and hip OA obtained in this study is comparable to other studies. Females have greater knee OA prevalence and a greater proportion of women have mobility limitations as well as hip and knee pain; it is important to target this sub-group.]]> Wed 11 Apr 2018 11:28:25 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45101 Wed 07 Feb 2024 17:04:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43939 Wed 05 Oct 2022 12:51:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50159 Wed 05 Jul 2023 15:35:23 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52167 Wed 04 Oct 2023 10:56:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27801 Wed 04 Apr 2018 17:04:59 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38912 Wed 02 Mar 2022 14:54:19 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54548 Tue 27 Feb 2024 20:42:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54481 Tue 27 Feb 2024 15:05:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54482 Tue 27 Feb 2024 15:04:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33281 Tue 25 Sep 2018 11:08:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41967 Tue 16 Aug 2022 14:45:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47938 Tue 11 Jul 2023 11:00:27 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:378 Tue 08 Jan 2019 15:22:58 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38998 Tue 05 Apr 2022 15:19:29 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38101 Tue 03 Aug 2021 19:03:43 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55008 Thu 28 Mar 2024 15:43:44 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:648 Thu 25 Jul 2013 09:10:27 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42577 Thu 25 Aug 2022 14:35:16 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25778 or ≥ 4 were available for 22 of these 24 studies (total n = 3491), and ranged from 25 to 85%. In random effects meta-analysis, the pooled prevalence estimate was 50% (95% CI 43-57%), with substantial heterogeneity (I² = 94%). Neither depression status nor time point post-stroke explained the heterogeneity between studies. In post-hoc analysis, fatigue prevalence was found to be lower in the four Asian studies (35%; 95% CI 20-50; I² = 96%). Conclusions: Our results confirm that fatigue is a widespread issue for stroke survivors, although it may be less prevalent in Asia. Further research is needed to explain the wide variability in prevalence estimates between studies.]]> Thu 24 Mar 2022 11:30:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36283 Thu 19 Mar 2020 17:51:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42115 Thu 18 Aug 2022 14:21:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29431 4 hours per day. Conclusions: Sedentary behaviour was associated with increased risk of all-cause mortality in people with CVD, independent of physical activity and other confounders. In addition to the promotion of regular physical activity, cardiac rehabilitation efforts which also focus on reducing sedentary behaviour may be beneficial.]]> Thu 17 Mar 2022 14:38:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34959 Thu 17 Mar 2022 14:33:22 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48866 Thu 13 Apr 2023 10:01:04 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48841 Thu 13 Apr 2023 09:46:22 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46049 P-value<0.05. Results. The average SBP and DBP were 124.98±17.18 mmHg and 78.92±10.13 mmHg, respectively. The prevalence of hypertension was 24.43% (95% CI: 21.57, 27.28). Majority (51.64%) of adults were not aware of their elevated blood pressure status. hypertension was significantly associated with the age group 30-44 (aOR 3.61, 95% CI: 2.0, 6.55), 45-54 (aOR 5.36, 95% CI: 2.62, 10.91), and 55-64 (aOR 9.38, 95% CI: 4.73, 18.59), being unemployed (aOR 1.68, 95%CI: 1.03, 2.77), ever smoking (aOR 1.89, 95% CI: 1.04, 2.23), having abdominal obesity (aOR 1.72, 95% CI: 1.13, 2.64), and BMI≥25 kg/m² (aOR 1.48, 95%CI: 1.01, 2.15). Conclusion. Moderately high prevalence of hypertension was observed among adults in study setting demonstrating a major public health problem. Majority of adults with hypertension in study setting were not aware of their elevated BP status highlighting the burden of the hidden morbidity and subsequent complications. Community level intervention and routine assessment of sociodemographic, behavioral, and biophysiological risk factors, screening, and diagnosis of NCDs should be institutionalized to address the occult burden.]]> Thu 10 Nov 2022 10:14:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52258 Thu 05 Oct 2023 14:13:27 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30971 Thu 04 Nov 2021 10:38:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41246 Sat 30 Jul 2022 12:33:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:376 Sat 24 Mar 2018 11:02:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8 Sat 24 Mar 2018 11:02:45 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8427 Sat 24 Mar 2018 08:40:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9405 12 on the EPDS and/or positive on the “interval symptom” question were then administered the CIDI. A further 65 randomly selected women that screened negative were also administered the CIDI. Loss to postnatal follow-up was very significant, and returns rates were inconsistent across the three postnatal time points. Almost 25% of those who screened positive did not complete a CIDI. For screen-positive status, a total of 314 (24.4%) of those that returned questionnaires (N=1,289) screened positive at least once across the 6- to 8-month interval. Of these, 79 were lost to follow-up; thus, 235 (74.8%) completed a CIDI. In this group, 34.7% had been positive both on the EPDS and the “interval” question, 15.9% on the EPDS alone, and 49.4% on the “interval” question alone. For the CIDI diagnosis and estimated 6- to 8-month period CIDI prevalence, among those 235 women who screened positive and completed a CIDI, 67.2% met the criteria for a CIDI diagnosis, as did 16.9% of those who screened negative. The breakdown in CIDI diagnoses in the 235 women was 32.8% major depression (± anxiety disorder); 26.4% minor depression alone; and 8.1% with a primary anxiety disorder (approximately half with minor depression). Put another way, 20.4% of these women had an anxiety disorder (approximately two thirds with comorbid depression) and 37.7% of women with a major depressive episode (MDE) had a comorbid anxiety disorder. The estimated 6- to 8-month prevalence rate for a CIDI diagnosis of anxiety or depression (major or minor) was 29.2% (95% CI 26.7%–31.7%). The use of the “interval symptom” question alone was 1.7 times more likely to identify positive CIDI cases than the EPDS alone. Almost 40% of postnatal women with a diagnosis of MDE have a comorbid diagnosis of anxiety disorder. The estimated 6- to 8-month period prevalence for CIDI cases of anxiety and depression was 29.2%. Screening for anxiety and depression using the EPDS alone was associated with a lesser capacity to identify CIDI caseness than a simple “interval symptom” question (for the 2 months prior) which almost doubled the yield. This paper demonstrates that combining the EPDS with the “interval symptom” question improves detection of CIDI caseness.]]> Sat 24 Mar 2018 08:39:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12779 300,000 employees. Employees with FD were compared to propensity-score-matched employees without FD (controls). Outcome measures included the prevalence, costs, and utilization of health services for comorbid conditions as defined by the Agency for Healthcare Research and Quality (AHRQ) and the odds ratios of having FD from a multivariate model. Results: FD employees (N = 1,669) and a 50:1 matched control cohort (N = 83,450) were compared. Compared to matched controls, FD employees were more likely to have all major diagnostic categories. Moreover, 199/261 of the AHRQ’s specific categories were more common in the FD cohort. Annual medical costs for the FD cohort were greater than for controls in 155/261 (59%) specific categories and significantly greater (P ≤ 0.05) in 76 categories (29%). Similarly, services were greater for 179/261 (69%) specific categories and significantly greater (P ≤ 0.05) in 110 categories (42%). In a multivariate model, esophageal disorders, gastritis and duodenitis, and abdominal pain were the most associated with having FD (odds ratios 3.8, 3.7, and 3.6, respectively). Only hypertension complications and disorders of the teeth and jaw were significantly negatively associated with FD.Conclusion: There is unexplained excess comorbidity associated with FD which may be a major determining factor for excess healthcare services and costs.]]> Sat 24 Mar 2018 08:18:19 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12765 Sat 24 Mar 2018 08:18:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10473 Sat 24 Mar 2018 08:09:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11163 Sat 24 Mar 2018 08:08:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20409 Sat 24 Mar 2018 08:00:51 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16887 Sat 24 Mar 2018 08:00:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20493 Sat 24 Mar 2018 07:59:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19125 C) were found. In addition, five variants predicted to be protein-affecting were also identified. Our study shows that the prevalence of PALB2 germline mutations in individuals with TNBC is ~1%, similar to the prevalence of PALB2 germline mutation of 1% in familial non-BRCA1/2 breast cancer cohorts.]]> Sat 24 Mar 2018 07:55:57 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19741 Sat 24 Mar 2018 07:53:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21369 Sat 24 Mar 2018 07:51:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21556 Sat 24 Mar 2018 07:49:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5431 Sat 24 Mar 2018 07:48:15 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:276 30% of mutations seem to cluster on proximal Xp and in the pericentric region. In a systematic screen of brain-expressed genes from this region in 210 families with XLMR, we identified seven different mutations in JARID1C, including one frameshift mutation and two nonsense mutations that introduce premature stop codons, as well as four missense mutations that alter evolutionarily conserved amino acids. In two of these families, expression studies revealed the almost complete absence of the mutated JARID1C transcript, suggesting that the phenotype in these families results from functional loss of the JARID1C protein. JARID1C (Jumonji AT-rich interactive domain 1C), formerly known as "SMCX," is highly similar to the Y-chromosomal gene JARID1D/SMCY, which encodes the H-Y antigen. The JARID1C protein belongs to the highly conserved ARID protein family. It contains several DNA-binding motifs that link it to transcriptional regulation and chromatin remodeling, processes that are defective in various other forms of mental retardation. Our results suggest that JARID1C mutations are a relatively common cause of XLMR and that this gene might play an important role in human brain function.]]> Sat 24 Mar 2018 07:43:03 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:191 Sat 24 Mar 2018 07:42:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:236 Sat 24 Mar 2018 07:42:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:324 Sat 24 Mar 2018 07:42:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:372 Sat 24 Mar 2018 07:42:30 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:74 Sat 24 Mar 2018 07:42:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55 Sat 24 Mar 2018 07:42:00 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47 Sat 24 Mar 2018 07:42:00 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27280 Sat 24 Mar 2018 07:40:22 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29982 Sat 24 Mar 2018 07:37:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4755 Sat 24 Mar 2018 07:21:07 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4784 Sat 24 Mar 2018 07:20:44 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4463 Sat 24 Mar 2018 07:18:29 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23721 Sat 24 Mar 2018 07:16:57 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25202 Sat 24 Mar 2018 07:14:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23757 Sat 24 Mar 2018 07:11:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23233 Sat 24 Mar 2018 07:10:35 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54592 Sat 02 Mar 2024 11:19:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39018 2DS₂-VA scheme, were calculated. Factors associated with AF were assessed using logistic regression. Results: From 2000 to 2015, a total of 1827 women with AF were identified. AF prevalence increased every year as women aged from 2.71% (95% CI 1.62%–3.80%) in 2000 among women aged 74–79 years to 24.83% (95% CI = 23.23%–26.44%) in 2015 among women aged 89–94 years. The incidence proportion remained constant (between 3% and 5%) throughout the study period. Sedentary lifestyle (OR = 1.24, 95% CI = 1.04–1.49), hypertension (OR = 1.24, 95% CI = 1.09–1.42), arthritis (OR = 1.24, 95% CI = 1.09–1.41), heart attack (OR = 1.62, 95% CI = 1.18–2.24), and angina (OR = 1.39, 95% CI = 1.14–1.70) were independently associated with AF. Mean CHA₂DS₂-VA score for women with AF was 3.43 (SD ± 1.23). Conclusions: The prevalence of AF reported in Australian women is among the highest compared to previous estimations from other countries and regions. According to the findings, about one in four women over the age of 90 years had AF. These women were also at high risk of stroke. This has significant public health implications especially with changing demographics of increase in the aging population. Further research is required on understanding how women with AF are treated in Australia and their health outcomes.]]> Mon 29 Jan 2024 17:43:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51240 Mon 28 Aug 2023 12:22:39 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43586 Mon 26 Sep 2022 12:31:48 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44801 Mon 24 Oct 2022 09:24:27 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32392 Mon 23 Sep 2019 10:46:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47552 Mon 23 Jan 2023 12:29:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53930 Mon 22 Jan 2024 16:50:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53785 Mon 15 Jan 2024 10:30:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53038 Mon 13 Nov 2023 09:02:15 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54178 Mon 12 Feb 2024 13:11:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21659 Mon 11 Mar 2019 12:16:36 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55063 65%) of students. Most students (mean age = 17) did not know that early sexual debut (before 18 years) is a risk factor for cervical cancer (72%) and that a blood test cannot detect cervical cancer (71%). Students in later stages of senior high school education and those who received sexual health education from teachers and parents had significantly greater cervical cancer knowledge scores than their counterparts. Interactive effects showed that school-based sexual health education was associated with higher knowledge scores than home-based education among students. Conclusions: Most female senior high school students had gaps in knowledge about cervical cancer prevention. Finding new ways to strengthen the capacity of schools and parents to deliver accurate cervical cancer prevention information is warranted.]]> Mon 08 Apr 2024 12:39:07 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46878 Mon 05 Dec 2022 12:35:32 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39340 Mon 03 Jul 2023 10:37:21 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33971 Fri 25 Jan 2019 14:41:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53116 Fri 17 Nov 2023 12:02:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19834 Fri 14 Aug 2015 13:26:22 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46120 Fri 11 Nov 2022 15:00:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38948 Fri 11 Mar 2022 12:45:18 AEDT ]]>